Metabolomics in Health Studies
Metabolites are already used as rapid diagnostic tools for a number of diseases, allowing early diagnosis and treatment, e.g.:
Metabolomics offers a powerful tool with which to study the effects of disease and drug treatments on the human body by:
The metabolome has been shown to be a particularly high-resolution method for amplifying and thereby reflecting changes in the levels of gene products, especially those which accompany disease pathogenesis.
It also offers an insight into how drugs function, and is an increasingly utilised tool in the early stages of drug development, especially where global changes in metabolite levels are monitored. Metabolomics offers a powerful tool for:
Metabolomic analysis involves the collection and analysis of biological fluids. Blood (serum or plasma) or urine are typically used since these are straight forward to collect and give a profile of the whole body.